As part of our drive to foster independent research skills and encourage inter-disciplinary learning at Wimbledon High School, our sixth formers have the opportunity to embark on novel research with professional scientists and data scientists across Europe.
Novel research is something that we most often associate with postgraduate studies – work that is contributing towards a DPhil, perhaps. Yet through some fascinating links to ‘real life’ scientists in the field, students at Wimbledon High School have the opportunity to delve deep into big data, to investigate a thesis and eventually publish their research. You can see an example in this video, and in the Big Data section below.
Under the expert guidance of our Dr Clare Roper, our Director of Science, Technology and Engineering, students may opt to crunch and analyse data sets on a topic of their choosing. Identifying trends, backing up their findings and presenting them in a professional academic format, with all the appropriate references, the students learn invaluable skills. Our links to real life science are broad and span various ages of student. Currently, we have these exciting projects underway:
· Using AlphaFold (machine learning protein folding algorithm) to predict the function of proteins involved in meiosis
· Exploring the impact of AlphaFold on the output from protein scientists
· Investigating the outcome of tie-breaks in elite male and female tennis matches
· Exploring the migratory patterns and the influence of global warming on a population of reindeer in Canada
· Comparing the potential of solar and hydroelectric power in Nepal
Recent projects:
Big Data Group
Recent projects:
Antonia: Investigating Caesarean Sections in the National Health Service in England
Athena worked with NHS data and sought advice from scientists at the NHS and the Department of Economics for her project.
Grace and Phoebe: Investigating the Effect of the ULEZ on NOx Concentrations in Central London
Grace and Phoebe worked with scientists from the School of Chemistry, University of Bristol, and worked with data from Air Quality Archive for their project.
One of our students, Lizzie B, published as an 18 year-old in the International Journal of Performance Analysis in Sport. (AELTC granted her access to a vast data set and she had mentoring from IBM); Poppy S published in the International RJLBPCS Journal and former WHS student Rhea S published on The Role of Replicase Polyprotein 1ab in SARS-CoV-2 in the YS Journal.
Bioinformatics Club
Recent projects:
How does ACE2 interact with the SARS-CoV-2 spike protein and how does this binding vary with different living organisms? In collaboration with scientists at the European Molecular Biology Laboratory, Heidelberg, Germany.
An investigation into the viral DNA in sewage water to model how we can predict pandemics, in collaboration with the University of Birmingham and MIT (Massachusetts Institute of Technology).
Proteins - investigating enzymes that digest nylon, which could have a positive impact on sustainability.
In spring/summer of 2020, European Molecular Biology Laboratory (EMBL), together with Dr. Clare Roper, organized a pilot bioinformatics course for secondary school students-Life in Numbers (LiNes).
Seven students from WHS, guided by EMBL scientists, bioinformaticians and Dr. Roper got an in depth look into the field of bioinformatics, the data available and the various tools used to study and interpret biological data. The students, with the help of EMBL scientists also formulated authentic research questions and undertook real research projects. One student studied the differences in proteins involved in immune function in red and grey squirrel populations, another student chose to study data generated as a result of the on-going pandemic as she investigated which mammalian species lack binding sites for the coronavirus (SARS-CoV-2) spike protein.
Physics students in Year 10 and Year 12 are working with students from our partner school Ricards Lodge on this University College London project looking at exoplanets. Watch this space…
Racket research
Recent projects:
Athena: The Impact of Converting Break Points on Match Success in Elite Female Tennis Players
Athena worked with sports scientists linked with the Wimbledon Championships to write her research paper and used data from All England Lawn Tennis Club.
You can listen to Athena discuss her research in the video below.
Eliza: A Faster Serve Has More Impact on Success for Female Elite Tennis Players than Males
Eliza worked with sport scientists linked with the Wimbledon Championships and used data from All England Lawn Tennis Club.
Sixth form biology: Darwin Tree of Life Project
We are involved in UK project to sequence all higher organisms across the UK with our new PCR (Polymerase Chain Reaction) machine. Once it is further developed, we will be involving partner schools next academic year.